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In the modern analyze, we reported the identification as well as characterization of a new atypical opioid receptor with special unfavorable regulatory Houses to opioid peptides.1 Our outcomes showed that ACKR3/CXCR7, hitherto referred to as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is likewise a broad-spectrum scavenger for